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What happens when you take paracetamol? 💊 Your liver gets to work breaking it down into harmless bits. But here's the twist... Those bits need a taxi (yep, a molecule called glutathione)
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Good ol' paracetamol: 'But an overconsumption takes its toll'
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A 48-hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https://bestpractice.bmj.com/topics/en-us/1010
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Refractory high anion gap metabolic acidosis due to chronic paracetamol use: a case report | Journal of Medical Case Reports
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Acetaminophen metabolism and NAPQI-mediated mitochondrial effects
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Fasting depletes Glutathione, turning "safe" Paracetamol doses into a liver-toxic emergency. Don't let a therapeutic dose become a lethal one. See the safety protocols on BMJ Best Practice via bio. 🔍 #MedEd #
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File:Paracetamol metabolism.svg
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