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Rational design of dual-agonist peptides targeting GLP-1 and NPY2 receptors for regulating glucose homeostasis and body weight with minimal nausea and emesis
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Pic1👉🏻Representation of SCFA & GLP-1 physiological roles.🧠SCFA-activated colonic FFA2 triggers⬆️gut motilliity,⬆️or⬇️insulin secretion,& stimulates the release of anorectic hormones PYY & GLP-1 from colonic crypts.GLP-1 in turn (i
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Patterns of colocalisation of GLP-1, GIP and PYY in enteroendocrine
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The Melanocortin-4 Receptor Is Expressed in Enteroendocrine L Cells and Regulates the Release of Peptide YY and Glucagon-like Peptide 1 In Vivo: Cell Metabolism
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Adenosine triphosphate is co-secreted with glucagon-like peptide-1 to modulate intestinal enterocytes and afferent neurons
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Upcoming wave of hormone-based therapies set to change field of diabetes, obesity care
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Advancements in Clinical Research and Development of Obesity Treatment Medications
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