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Emerging Weight Loss Medications: What You Need to Know Activated Health & Wellness GLP 1 Promoting Foods Dr. Rachel Paul New aspects of an old drug: metformin as a glucagon like peptide 1 (GLP 1) enhancer and sensitiser Diabetologia Springer Nature Link One of the world's most talked about medicines owes a lot to a venomous lizard. Researchers studying the saliva of the Gila monster discovered a molecule similar to GLP 1. That discovery helped Semaglutide and tirzepatide are both GLP 1 medications but they're not the same. Semaglutide works on one hormone (GLP 1) to reduce appetite and slow digestion. Tirzepatide works on two hormones ( LY3437943, a novel triple glucagon, GIP, and GLP 1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept: Cell Metabolism