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Reviewed in the United States on May 29, 2026
glp-1 and dopamine Substack Series 2 of 6, GLP-1 Receptor Agonists: Mechanisms and Clinical Applications
Marsoni
M251S
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💡 New insight in diabetes care: In patients with T2DM and ASCVD, the SURPASS-CVOT trial found that tirzepatide was noninferior to dulaglutide for major cardiovascular events (12.2% vs 13.1%; HR 0.92). What
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In the SURPASS-CVOT head-to-head trial involving over 13,000 adults with T2D and ASCVD, tirzepatide (Mounjaro) matched dulaglutide in reducing major cardiovascular events (8% lower risk) and significantly cut all-cause mortality by 16%
20.23