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Semaglutide ameliorates cognition and glucose metabolism dysfunction in the 3xTg mouse model of Alzheimer's disease via the GLP-1R/SIRT1/GLUT4 pathway
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The evoke and evoke+ Phase 3 trials found that oral semaglutide was not superior to placebo in reducing the progression of Alzheimer's disease in patients with early-stage symptomatic disease, leading to the
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evoke and evoke+: design of two large‐scale, double‐blind, placebo‐controlled, phase 3 studies evaluating the neuroprotective effects of semaglutide in early Alzheimer's disease - Atri - 2022 - Alzheimer's & Dementia
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