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Tirzepatide vs Retatrutide: Comparing Weight Loss Efficacy and Safety Tyde Wellness Semaglutide vs. Tirzepatide: Which GLP 1 Is Right for You? Most 'slow responders' to tirzepatide achieve 5% or greater weight reduction at 72 weeks Postmenopausal women on the GLP 1 medication tirzepatide (Zepbound) for obesity lost more weight if they were also using menopause hormone therapy, a retrospective cohort study indicated. https: www.medpagetoday.com endocrinology menopause 119594 Daniel 1 year on GLP 1 (compounded Tirzepatide) From 221 180 185 lbs 5mg is my sweet spot7.5 had me avoiding the fridge like it owed me money . Only Tirzepatide, similar to semaglutide and Ozempic, mimick a hormone called GLP 1 & GIP which regulate blood sugar levels and appetite. This helps you lose weight. Tirzepatide is meant to be a tool