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GIPR antagonist antibodies conjugated to GLP 1 peptide are bispecific molecules that decrease weight in obese mice and monkeys: Cell Reports Medicine Oral GLP 1 Drops BloomMD Supplement manufacturers have capitalized on the explosive popularity of diabetes control and weight loss drugs such as Ozempic, Wegovy and Zepbound by flooding the market with their own pills, D Allulose Regulates Obesity via Endoplasmic Reticulum Stress Mediated Glucagon Like Peptide 1 Receptor Pathway Geum Hwa Lee, Hwa Young Lee, Young Jae Lim, Ji hyun Kim, So Young Rah, Myung Ja Chung, Se Young Park, Soonok Sa, Hyewon Some patients have reported a kind of emotional flattening while on GLP 1 drugs. Online, the phenomenon has taken on a name anhedonia and, more colloquially, Ozempic personality. GLP 1 receptor agonist exendin 4 suppresses food intake by inhibiting hindbrain orexigenic NPY neurons American Journal of Physiology Endocrinology and Metabolism American Physiological Society