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clinical trials semaglutide Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial

Marsoni M251S
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4.7 ★★★★★
Based on 1362 reviews
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Vonda Kioultzopoulos
Waukegan, US
★★★★★ 3
Effective but may be uncomfortable
Color: Pink & Beige, Size: Medium/Large(fits size 8 to 11)
I have eczema on my feet and use a prescription cream that I leave on overnight. I often have a problem sleeping in socks but the silicone feels cool on my feet. The only drawback I have is the opening of the socks feel very tight around my ankles making them uncomfortable on me. I wish the opening was a bit more flexible.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 20, 2025
T
Verified Purchase
Tessy
Omaha, US
★★★★★ 1
Burned my already sensitive feet, too big
Color: Pink & Beige, Size: Medium/Large(fits size 8 to 11)
Feels icky, and the heat gets trapped and literally felt like my feet were being burned by these. The bottoms of these feel prickly and they are way too big. You have to sit still and cannot walk in them.
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Reviewed in the United States on April 22, 2026
M
Verified Purchase
Ms. Mac
Fort Morgan, US
★★★★★ 5
Just as good as paraffin wax
Color: Pink & Beige, Size: Medium/Large(fits size 8 to 11)
I might prefer these socks over paraffin wax. They are comfy and very moisturizing. I use these socks once a week to keep the heels and soles of my feet moisturized between pedicures. I rinse with warm, soapy water then hang to dry. They are hard to walk in, but there's a saying printed in the socks that's says something to the effect of "take a break, stay off your feet" lol I love that as a reminder to put my feet up and relax
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Reviewed in the United States on April 9, 2026
S
Verified Purchase
SKI
Fort Morgan, US
★★★★★ 5
Love these!
Color: Pink & Beige, Size: Small(fits up to size 7)
Love these! As I write this review, I’m sitting in my recliner with these on. I have had other silicone socks in the past and would like to share a few of the things that I have learned. These fit great! The others were 2-3 sizes too big because you could not order a size. I wear a size 7 women’s shoe. I got the smaller size. I walked around my apartment in my old ones and they got kinda yucky. Now, I sit in my recliner, put them on and chill for a few hours. I now take them off and put in a ziplock bag so they stay nice and clean (no cat hair!). I use them once a week usually on Saturday or Sunday as I’m a working girl. Also, I use Auqaphor before I put them on and put cotton socks on after I’m finished. Your feet will be SO soft. This is not a one and done…I do this every week especially during sandal season! I know this was lengthy and I hope you got some tips.
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Reviewed in the United States on April 25, 2026
R
Verified Purchase
Ryan or Rachel Torkelson
West Palm Beach, US
★★★★★ 5
So excited for results, feels like it’s working!
Size: Medium, Unit Count: 4
First time trying them right now as delivered today. Originally thought was supposed to wear all night but glad to find out 30 minutes just because my dog sleeps on my feet over my sheets! These silicone socks feel great and I trim my toe nails short enough they seem very durable and unlikely to rip like the pic review shows. I am confident my feet and heels will much smoother after first time wearing! I do have acrylic nails so I will be careful Putting the silicone socks on and off. Just as easy as the video the spread the lotion inside the socks and rub it around, mess free!!
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Reviewed in the United States on January 18, 2026

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